RAB7B antibody
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- Target See all RAB7B Antibodies
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAB7B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- RAB7B, member RAS oncogene family
- Isotype
- IgG
- Top Product
- Discover our top product RAB7B Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- Alternative Name
- RAB7B (RAB7B Products)
- Synonyms
- RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody
- Background
- Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
- Gene ID
- 338382
- UniProt
- Q96AH8
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