TPM3 antibody

Catalog No. ABIN5698646

The Rabbit Polyclonal anti-TPM3 antibody has been validated for WB, IHC, ELISA and IP. It is suitable to detect TPM3 in samples from Human, Mouse and Rat.

Quick Overview for TPM3 antibody (ABIN5698646)

Target: TPM3 (Tropomyosin 3 (TPM3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-TPM3 Antibody

Immunogen: tropomyosin 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab08890(TPM3 antibody) at dilution of 1:800

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TPM3

Target: TPM3 (Tropomyosin 3 (TPM3))

Alternative Name: TPM3

Background: Synonyms:CAPM1, CFTD, HEL-189, HEL-S-82p, hscp30,NEM1, OK/SW-cl.5, TM-5,TM3, TM30, TM30nm, TM5, TPMsk3, TRK Background:This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

Gene ID: 7169

UniProt: P06753