UMPS antibody
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- Target See all UMPS Antibodies
- UMPS (Uridine Monophosphate Synthetase (UMPS))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UMPS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- uridine monophosphate synthetase
- Isotype
- IgG
- Top Product
- Discover our top product UMPS Primary Antibody
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- Application Notes
- WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09253(UMPS antibody) at dilution of 1:400
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- UMPS (Uridine Monophosphate Synthetase (UMPS))
- Alternative Name
- UMPS (UMPS Products)
- Synonyms
- zgc:55702 antibody, zgc:55723 antibody, UMPS antibody, OPRT antibody, 1700095D23Rik antibody, AA408257 antibody, AL033308 antibody, BB164745 antibody, Orotidine 5'-phosphate decarboxylase antibody, uridine monophosphate synthetase antibody, uridine monophosphate synthetase L homeolog antibody, uridine 5'-monophosphate synthase antibody, umps-1 antibody, umps antibody, umps.L antibody, UMPS antibody, LOC100556619 antibody, Umps antibody
- Background
- Synonyms:OMPdecase, OPRT, OPRTase, UMPS Background:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
- Molecular Weight
- 26kDa
- Gene ID
- 7372
- UniProt
- P11172
- Pathways
- Ribonucleoside Biosynthetic Process
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