Plexin B2 antibody

Catalog No. ABIN5698971

Product Details anti-Plexin B2 Antibody

Target: Plexin B2 (PLXNB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin B2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Immunogen: plexin B2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Plexin B2

Target: Plexin B2 (PLXNB2)

Alternative Name: Plexin B2 (PLXNB2 Products)

Background: Synonyms:KIAA0315, MM1, Nbla00445, PLEXB2, Plexin B2, PLXNB2 Background:Semaphorins, originally identified as axon guidance molecules, have also been implicated in angiogenesis, immunoregulation, and cancer (PMID: 16584533). Plexins are main receptors for semaphorins and are thought to control many of the functional effects of semaphorins. PLXNB2 is one of the three plexin-B family members which participate in axon guidance and cell migration in response to semaphorins. It has been reported that plexin B2 precursor is 240 kDa and can be cleaved into alpha subunit (~170- kDa) and beta subunit (80- kDa) (PMID: 12533544).

Pathways: Tube Formation