Fatty Acid Synthase antibody
Quick Overview for Fatty Acid Synthase antibody (ABIN5700876)
Target
See all Fatty Acid Synthase (FASN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- FASN antibody
-
Immunogen
- fatty acid synthase
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze / thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- -20°C for 12 months
-
Expiry Date
- 12 months
-
-
- Fatty Acid Synthase (FASN)
-
Alternative Name
- FASN
-
Background
-
Synonyms: Fatty acid synthase|Type I fatty acid synthase|FASN|FAS
Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
-
Molecular Weight
- 250-272 kDa
-
Gene ID
- 2194
-
UniProt
- P49327
-
Pathways
- AMPK Signaling
Target
-