DHDDS antibody

Catalog No. ABIN5701537

This Rabbit Polyclonal antibody specifically detects DHDDS in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DHDDS antibody (ABIN5701537)

Target: DHDDS (Dehydrodolichyl Diphosphate Synthase (DHDDS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHDDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DHDDS Antibody

Purpose: DHDDS antibody

Immunogen: dehydrodolichyl diphosphate synthase

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DHDDS

Target: DHDDS (Dehydrodolichyl Diphosphate Synthase (DHDDS))

Alternative Name: DHDDS

Background:

Synonyms: Dehydrodolichyl diphosphate synthase complex subunit DHDDS|Cis-isoprenyltransferase (CIT, Cis-IPTase)|Cis-prenyltransferase subunit hCIT|Epididymis tissue protein Li 189m|DHDDS|HDS

Background: With DHDDS, forms the dehydrodolichyl diphosphate synthase(DDS) complex, an essential component of the dolichol monophosphate(Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate(IPP) to farnesyl pyrophosphate(FPP) to produce dehydrodolichyl diphosphate(Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum(ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.

Molecular Weight: 34 kDa

Gene ID: 79947

UniProt: Q86SQ9