DHDDS antibody
Quick Overview for DHDDS antibody (ABIN5701537)
Target
See all DHDDS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- dehydrodolichyl diphosphate synthase
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- DHDDS (Dehydrodolichyl Diphosphate Synthase (DHDDS))
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Alternative Name
- DHDDS
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Background
- Synonyms:HDS Background:With DHDDS, forms the dehydrodolichyl diphosphate synthase(DDS) complex, an essential component of the dolichol monophosphate(Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate(IPP) to farnesyl pyrophosphate(FPP) to produce dehydrodolichyl diphosphate(Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum(ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.
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Molecular Weight
- 34 kDa
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Gene ID
- 79947
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UniProt
- Q86SQ9
Target
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