STING1 (AA 66-347) antibody

Catalog No. ABIN7825879

The Rabbit Polyclonal anti-STING1 antibody is suitable to detect STING1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, FACS, IF and ICC.

Quick Overview for STING1 (AA 66-347) antibody (ABIN7825879)

Target: STING1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details

Binding Specificity: AA 66-347

Purpose: Anti-TMEM173/STING Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-TMEM173/STING Antibody catalog # A01871-3. Tested in WB, IHC, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMEM173/STING recombinant protein (Position: L66-K347). Human TMEM173/STING shares 72.5% and 71.9% amino acid (aa) sequence identity with mouse and rat TMEM173/STING, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: STING1

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Molecular Weight: 36 kDa

Gene ID: 340061