H2AC18 (AA 1-130) antibody

Catalog No. ABIN5703706

This Rabbit Polyclonal antibody specifically detects in ELISA, IHC and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for H2AC18 (AA 1-130) antibody (ABIN5703706)

Target: H2AC18

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Binding Specificity: AA 1-130

Purpose: H2AC18 antibody

Immunogen:

Immunogen sequence: 1-130aa

Immunogen: histone cluster 2, H2aa4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

L02 cells were subjected to SDS PAGE followed by western blot with FNab03879( HIST2H2AA4 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: H2AC18

Background:

Synonyms: Histone H2A type 2-A|H2A-clustered histone 18|H2A-clustered histone 19|Histone H2A.2|Histone H2A/o|H2AC18|H2AFO|HIST2H2AA|HIST2H2AA3

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Molecular Weight: 14 kDa

Gene ID: 8337

UniProt: Q6FI13