MMP1 antibody

Catalog No. ABIN5703938

The Rabbit Polyclonal anti-MMP1 antibody is suitable to detect MMP1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, IP, IF and FACS.

Quick Overview for MMP1 antibody (ABIN5703938)

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-MMP1 Antibody

Purpose: MMP1 antibody

Immunogen:

Immunogen sequence: 23- 215aa

Immunogen: matrix metallopeptidase 1 (interstitial collagenase)

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000 IP :1:500-1:5000 IHC : 1:100-1:400 IF : 1:20-1:200

Comment:

A549 cells were subjected to SDS PAGE followed by western blot with FNab05233(MMP1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MMP1

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Alternative Name: MMP1

Background:

Synonyms: Interstitial collagenase|Fibroblast collagenase|Matrix metalloproteinase-1 (MMP-1)|22 kDa interstitial collagenase|27 kDa interstitial collagenase|MMP1|CLG

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molecular Weight: 54 kDa,62 kDa

Gene ID: 4312

UniProt: P03956