PEX5 antibody

Catalog No. ABIN5704976

The Rabbit Polyclonal anti-PEX5 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect PEX5 in samples from Human, Mouse and Rat.

Quick Overview for PEX5 antibody (ABIN5704976)

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-PEX5 Antibody

Purpose: PEX5 antibody

Immunogen: peroxisomal biogenesis factor 5

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000 IP : 1:200-1:2000 IHC : 1:100-1:400 IF : 1:50-1:500

Comment:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab06331(PEX5 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PEX5

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Alternative Name: PEX5

Background:

Synonyms: Peroxisomal targeting signal 1 receptor (PTS1 receptor, PTS1R)|PTS1-BP|Peroxin-5|Peroxisomal C-terminal targeting signal import receptor|Peroxisome receptor 1|PEX5|PXR1

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 70 kDa

Gene ID: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process