ENO2/NSE antibody

Catalog No. ABIN570656

The Rabbit Polyclonal anti-ENO2/NSE antibody is suitable to detect ENO2/NSE in samples from Human. It has been validated for WB and IF.

Quick Overview for ENO2/NSE antibody (ABIN570656)

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENO2/NSE antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ENO2/NSE Antibody

Cross-Reactivity: Human

Purification: purified

Immunogen: Purified recombinant full length human NSE protein from E. coli.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for ENO2/NSE

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Alternative Name: NSE (Neuron Specific Enolase)

Background: Human Neuron specific enolase (NSE) (EC 4. 2. 1. 11) is a 47,138 dalton protein (434 amino acids) expressed in neurons of the peripheral nervous system (PNS) and central nervous system (CNS). NSE catalyzes the conversion of 2-phospho-Dglycerate into phosphoenol pyruvate, and is an essential enzyme in energy metabolism in nervous tissues. NSE corresponds to ENO2 or enolase gamma and is heavily expressed in neuronal cells, developing neuronal lineage and neuroendocrine cells. Release of NSE from damaged neurons into CSF and blood has also been used as a biomarker of neuronal injury.