Recombinant Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) antibody

Catalog No. ABIN5707604

This Rabbit Monoclonal antibody specifically detects Human Papilloma Virus 16 Capsid Protein in IHC (p). It exhibits reactivity toward Human Papillomavirus 16 (HPV-16).

Quick Overview for Recombinant Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) antibody (ABIN5707604)

Target: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Antibody Type: Recombinant Antibody

Reactivity: Human Papillomavirus 16 (HPV-16)

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HPV16-2058R

Product Details

Purpose: Recombinant HPV16 L1 Antibody / Rabbit Monoclonal

Purification: Protein A affinity chromatography

Immunogen: Human papilloma virus type 16, major capsid protein L1, was used as the immunogen for the recombinant HPV16 L1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant HPV16 L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant HPV16 L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Alternative Name: HPV16 L1

Target Type: Viral Protein

Background: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

UniProt: P03101