Glypican 3 antibody

Catalog No. ABIN5707609

This anti-Glypican 3 antibody is a Rabbit Monoclonal antibody detecting Glypican 3 in IHC (p). Suitable for Human.

Quick Overview for Glypican 3 antibody (ABIN5707609)

Target: Glypican 3 (GPC3)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glypican 3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SGPN3-2R

Product Details anti-Glypican 3 Antibody

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Glypican 3 antibody.

Isotype: IgG kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant Glypican 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Glypican 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Glypican 3

Target: Glypican 3 (GPC3)

Alternative Name: Glypican 3 / GPC3

Background: Glypican-3 is a proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. [UniProt]

Pathways: Glycosaminoglycan Metabolic Process