Recombinant Involucrin antibody

Catalog No. ABIN5707639

The Rabbit Monoclonal anti-Involucrin antibody (Clone IVRN-2113R) (ABIN5707639) specifically detects Involucrin in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Involucrin antibody (ABIN5707639)

Target: Involucrin (IVL)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Involucrin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: IVRN-2113R

Product Details anti-Involucrin Antibody

Purpose: Recombinant Involucrin Antibody (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: Involucrin purified from human keratinocytes was used as the immunogen for the recombinant Involucrin antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Titering of the recombinant Involucrin antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Involucrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Involucrin

Target: Involucrin (IVL)

Alternative Name: Involucrin

Background: Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. [Wiki]

UniProt: P07476