Recombinant FTL antibody (Light Chain)

Catalog No. ABIN5708056

The Rabbit Monoclonal anti-FTL antibody (Clone FTL-2338R) (ABIN5708056) specifically detects FTL in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant FTL antibody (Light Chain) (ABIN5708056)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-2338R

Product Details anti-FTL Antibody

Binding Specificity: AA 38-165, Light Chain

Purpose: Recombinant Ferritin Light Chain Antibody / Rabbit Monoclonal

Purification: Protein A affinity chromatography

Immunogen: Amino acids 38-165 of human FTL1 were used as the immunogen for this recombinant Ferritin Light Chain antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Ferritin Light Chain antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Ferritin Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: FTL1 / Ferritin light chain

Background: The FTL gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. This gene has multiple pseudogenes.

Although ferritin light chain has no ferroxidase activity, the light chain may be responsible for the electron transfer across the ferritin protein cage. [Wiki]

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis