NAT10 antibody (N-Term)

Catalog No. ABIN5708177

Product Details anti-NAT10 Antibody

Target: NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))

Binding Specificity: AA 146-178, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAT10 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 146-178 from human NAT10 was used as the immunogen for the NAT10 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the NAT10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NAT10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NAT10

Target: NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))

Alternative Name: ALP / N-acetyltransferase-like protein / NAT10 (NAT10 Products)

Synonyms: ALP antibody, NET43 antibody, AI429152 antibody, zgc:66119 antibody, DDBDRAFT_0190093 antibody, DDBDRAFT_0234062 antibody, DDB_0190093 antibody, DDB_0234062 antibody, RGD1306717 antibody, N-acetyltransferase 10 antibody, N-acetyltransferase 10 (GCN5-related) antibody, ribosome biogenesis ATPase (predicted) antibody, hypothetical protein antibody, N-acetyltransferase 10 (GCN5-related) L homeolog antibody, NAT10 antibody, Nat10 antibody, nat10 antibody, CC1G_12871 antibody, MCYG_05927 antibody, PITG_19671 antibody, MGYG_06040 antibody, SPAC20G8.09c antibody, nat10.L antibody

Background: NAT10 has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.

UniProt: Q9H0A0