Recombinant PLAP antibody (N-Term)

Catalog No. ABIN5708191

The Rabbit Monoclonal anti-PLAP antibody (Clone RM317) (ABIN5708191) specifically detects PLAP in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant PLAP antibody (N-Term) (ABIN5708191)

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PLAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RM317

Product Details anti-PLAP Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: A peptide corresponding to the N-terminus of human placental alkaline phosphatase was used as the immunogen for the recombinant PLAP antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant PLAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunohistochemistry (FFPE): 1:500-1:1000,Western Blot: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Buffer: Antibody in PBS with 50 % Glycerol, 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the recombinant PLAP antibody at -20°C.

Target Details for PLAP

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Alternative Name: PLAP / Placental Alkaline Phosphatase

Background: Alkaline phosphatase, placental type is a membrane-bound glycosylated dimeric enzyme, also referred to as the heat-stable form, that is expressed primarily in the placenta, although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.

PLAP is a tumor marker, especially in seminoma and ovarian cancer. PLAP is reliable only in non-smokers, as smoking interferes with measurement of PLAP, since serum concentrations of PLAP are increased up to 10-fold in smokers and its measurement is therefore of little value in this group. [Wiki]

UniProt: P05187