Neuromedin U antibody

Catalog No. ABIN5708261

This Rabbit Polyclonal antibody specifically detects Neuromedin U in WB. It exhibits reactivity toward Rat and Mouse.

Quick Overview for Neuromedin U antibody (ABIN5708261)

Target: Neuromedin U (NMU)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuromedin U antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neuromedin U Antibody

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: Amino acids FRVDEEFQSPFASQSRGYFLFRPRN from the human protein were used as the immunogen for the NMU antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NMU antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the NMU antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Neuromedin U

Target: Neuromedin U (NMU)

Alternative Name: NMU / Neuromedin-U

Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

UniProt: P48645

Pathways: Feeding Behaviour, Photoperiodism