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TLR9 antibody (AA 830-880)

TLR9 Reactivity: Human WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN571375
  • Target See all TLR9 Antibodies
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Binding Specificity
    • 19
    • 15
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 830-880
    Reactivity
    • 93
    • 39
    • 13
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 63
    • 33
    • 7
    • 4
    • 1
    Rabbit
    Clonality
    • 71
    • 37
    Polyclonal
    Conjugate
    • 61
    • 13
    • 12
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR9 antibody is un-conjugated
    Application
    • 76
    • 49
    • 44
    • 44
    • 23
    • 15
    • 12
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Specificity
    Specific for TLR9.
    Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from AA 830-880 of human TLR9 conjugated to blue carrier protein was used as the antigen.
    Isotype
    IgG
    Top Product
    Discover our top product TLR9 Primary Antibody
  • Application Notes
    IHC, WB, Flow Cyt. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Alternative Name
    TLR9 (TLR9 Products)
    Synonyms
    CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
    Background
    FUNCTION: Participates in the innate immune response to microbial agents. Detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. SUBCELLULAR LOCATION: Membrane, Single-pass type II membrane protein. TISSUE SPECIFICITY: Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.,Innate Immunity,Toll-like receptor 9
    UniProt
    Q9NR96
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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