Aurora Kinase B antibody (pThr232)

Catalog No. ABIN574162

This Rabbit Polyclonal antibody specifically detects Aurora Kinase B in WB, IHC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Cow and Pig.

Quick Overview for Aurora Kinase B antibody (pThr232) (ABIN574162)

Target: Aurora Kinase B (AURKB)

Reactivity: Human, Mouse, Rat, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Aurora Kinase B Antibody

Binding Specificity: pThr232

Brand: IHC-plus™

Specificity: Detects an -40 kD protein, corresponding to the apparent molecular mass of phosphorylated Aurora B (AIM) (Thr232) on SDS-PAGE immunoblots, in samples from human origin. This antibody also detects a protein band at -35 kD predicted to be Aurora C.

Purification: Immunoaffinity purified

Immunogen: A synthetic phosphopeptide corresponding to amino acids surrounding Thr232 of human Aurora B (AIM), coupled to KLH.

Type of Immunogen: Synthetic phospho-peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (1 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum product recovery, after thawing, centrifuge the product vial before removing cap.

Storage: -20 °C

Storage Comment: Store at -20°C. Storage below -20°C is not recommended. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: AURKB / Aurora-B

Background: Name/Gene ID: AURKB
Subfamily: Aurora/IPL1-like
Family: Protein Kinase

Synonyms: AURKB, AIRK2, AIK2, Aurora kinase B, Aurora kinase B-Sv1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, ARK-2, ARK2, Aurkb-sv1, Aurkb-sv2, Aurora 1, Aurora-B, AIM-1, IPL1, STK-1, STK5, PPP1R48, AurB, Aurora B, Aurora kinase B-Sv2, Aurora-1, Aurora1, Serine/threonine kinase 12, STK1, STK12

Gene ID: 9212

UniProt: Q96GD4

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades