CTNNB1 antibody
Quick Overview for CTNNB1 antibody (ABIN574434)
Target
See all CTNNB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Brand
- IHC-plus™
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Specificity
- The antibody EM-22 reacts with C-terminal part of beta-catenin, an 88 kD multifunctional protein involved both in cell adhesion and in activation of transcription.
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Purification
- Protein A purified
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Immunogen
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Recombinant human beta-catenin.
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
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Approved: Flo, ICC, IHC, IHC-P (10 μg/mL), IP, WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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Alternative Name
- CTNNB1 / Beta Catenin
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Background
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Name/Gene ID: CTNNB1
Family: Catenin
Synonyms: CTNNB1, Beta-catenin, Catenin beta-1, CTNNB, Beta Catenin -
Gene ID
- 1499
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UniProt
- P35222
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Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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