BMP10 antibody (AA 86-96)
Quick Overview for BMP10 antibody (AA 86-96) (ABIN576109)
Target
See all BMP10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 86-96
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Specificity
- Recognizes Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily. BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.
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Purification
- Ammonium sulfate precipitation
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Immunogen
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Synthetic peptide from human BMP10.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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Alternative Name
- BMP10 / BMP-10
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Background
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Name/Gene ID: BMP10
Family: TGF beta
Synonyms: BMP10, BMP-10, Bone morphogenetic protein 10 -
Gene ID
- 27302
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UniProt
- O95393
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Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
Target
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