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BMP10 antibody (Internal Region)

BMP10 Reactivity: Human WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256960
  • Target See all BMP10 Antibodies
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Binding Specificity
    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 55
    • 26
    • 25
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 48
    • 7
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    • 6
    Polyclonal
    Conjugate
    • 35
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMP10 antibody is un-conjugated
    Application
    • 49
    • 16
    • 14
    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    BMP10 Antibody detects endogenous levels of total BMP10.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product BMP10 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Alternative Name
    BMP10 (BMP10 Products)
    Synonyms
    BMP10 antibody, si:dkey-13n15.5 antibody, Bmp10 antibody, BMP9 antibody, BMP-10 antibody, bone morphogenetic protein 10 antibody, BMP10 antibody, bmp10 antibody, LOC662386 antibody, Bmp10 antibody
    Background

    Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

    Gene: BMP10

    Molecular Weight
    48 kDa
    Gene ID
    27302
    UniProt
    O95393
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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