Tyrosine Hydroxylase antibody

Catalog No. ABIN576288

The Rabbit Polyclonal anti-Tyrosine Hydroxylase antibody (ABIN576288) specifically detects Tyrosine Hydroxylase in WB, IHC, IF and IHC (fro). The antibody is reactive with Rat and Mammalian samples.

Quick Overview for Tyrosine Hydroxylase antibody (ABIN576288)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Rat, Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Tyrosine Hydroxylase Antibody

Specificity: Recognizes tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Purification: Purified

Immunogen: Tyrosine hydroxylase purified from pheochromocytoma.

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:1000), IHC, IHC-Fr (1:1000), WB (1:1000)

Usage: Western Blot: LS-C43105 detects a band of approximately 60kD in rat caudate cell lysates.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: TH / Tyrosine Hydroxylase

Background: Name/Gene ID: TH
Family: Monooxygenase

Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

Gene ID: 7054

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour