Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Tyrosine Hydroxylase antibody

This anti-Tyrosine Hydroxylase antibody is a Rabbit Polyclonal antibody detecting Tyrosine Hydroxylase in WB, IHC, IF and IHC (fro). Suitable for Rat and Mammalian.
Catalog No. ABIN576288

Quick Overview for Tyrosine Hydroxylase antibody (ABIN576288)

Target

See all Tyrosine Hydroxylase (TH) Antibodies
Tyrosine Hydroxylase (TH)

Reactivity

  • 123
  • 121
  • 99
  • 10
  • 10
  • 9
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Rat, Mammalian

Host

  • 120
  • 37
  • 7
  • 6
  • 2
Rabbit

Clonality

  • 124
  • 46
  • 1
Polyclonal

Conjugate

  • 120
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Tyrosine Hydroxylase antibody is un-conjugated

Application

  • 124
  • 91
  • 42
  • 33
  • 32
  • 27
  • 22
  • 16
  • 14
  • 13
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Specificity

    Recognizes tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

    Purification

    Purified

    Immunogen

    Tyrosine hydroxylase purified from pheochromocytoma.

    Isotype

    IgG
  • Application Notes

    Approved: IF (1:1000), IHC, IHC-Fr (1:1000), WB (1:1000)

    Usage: Western Blot: LS-C43105 detects a band of approximately 60kD in rat caudate cell lysates.

    Comment

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM HEPES,  pH 7.5, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    Tyrosine Hydroxylase (TH)

    Alternative Name

    TH / Tyrosine Hydroxylase

    Background

    Name/Gene ID: TH
    Family: Monooxygenase

    Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

    Gene ID

    7054

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
You are here:
Chat with us!