ADK antibody (AA 22-362)

Catalog No. ABIN5775897

This Mouse Monoclonal antibody specifically detects ADK in WB, ELISA, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for ADK antibody (AA 22-362) (ABIN5775897)

Target: ADK (Adenosine Kinase (ADK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT4F8

Product Details anti-ADK Antibody

Binding Specificity: AA 22-362

Purpose: Human Adenosine Kinase/ADK antibody

Purification: Purified

Immunogen: Recombinant human ADK (22-362aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for ADK

Target: ADK (Adenosine Kinase (ADK))

Alternative Name: Adenosine Kinase/ADK

Background: Adenosine kinase (ADK) is the key regulator of adenosine metabolism. Because of the manifold receptor-dependent actions of adenosine, tight regulation of adenosine levels is crucial. The intracellular and extracellular pools of adenosine are in dynamic exchange by equilibrative and concentrative nucleoside transporters, so extracellular concentrations of adenosine are regulated by interplay of theses transporters with intracellular and extracellular enzymes of adenosine metabolism. Thus, the extracellular concentration of adenosine is enhanced by inhibition of equilibrative nucleoside transporters such as S- (4-nitrobenzyl) -6-thioinosine and cannabidiol and, stimulation of extracellular ATP breakdown and inhibition of intracellular adenosine removal.

NCBI Accession: NP_006712

Pathways: Ribonucleoside Biosynthetic Process