Cathepsin S antibody (AA 17-331)

Catalog No. ABIN5775924

This Mouse Monoclonal antibody specifically detects Cathepsin S in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for Cathepsin S antibody (AA 17-331) (ABIN5775924)

Target: Cathepsin S (CTSS)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cathepsin S antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT1F9

Product Details anti-Cathepsin S Antibody

Binding Specificity: AA 17-331

Purpose: Human Cathepsin S antibody

Purification: Purified

Immunogen: Recombinant human CTSS (17-331aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Cathepsin S

Target: Cathepsin S (CTSS)

Alternative Name: Cathepsin S

Background: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

NCBI Accession: NP_004070

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades