CACYBP antibody (AA 1-185)

Catalog No. ABIN5775925

The Mouse Monoclonal anti-CACYBP antibody is suitable to detect CACYBP in samples from Human. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for CACYBP antibody (AA 1-185) (ABIN5775925)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACYBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT3G8

Product Details anti-CACYBP Antibody

Binding Specificity: AA 1-185

Purpose: Human CACYBP antibody

Purification: Purified

Immunogen: Recombinant human CACYBP (1-185aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Alternative Name: CACYBP

Background: CACYBP (Calcyclin-binding protein) is primarily a nuclear protein that contains one CS domain and one SGS domain. CACYBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.

NCBI Accession: NP_001007215

Pathways: Response to Growth Hormone Stimulus