DNAL1 antibody (AA 1-190)

Catalog No. ABIN5775936

This Mouse Monoclonal antibody specifically detects DNAL1 in WB, ELISA, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for DNAL1 antibody (AA 1-190) (ABIN5775936)

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNAL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT29E4

Product Details anti-DNAL1 Antibody

Binding Specificity: AA 1-190

Purpose: Human DNAL1 antibody

Purification: Purified

Immunogen: Recombinant human DNAL1 (1-190aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for DNAL1

Target: DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

Alternative Name: DNAL1

Background: DNAL1, also known as dynein light chain 1 axonemal, is component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Homozygous mutations in the DNAL1 gene are associated with primary ciliary dyskinesia 16 (CILD16) which is a disorder characterized by abnormalities of motile cilia.

NCBI Accession: NP_113615