PKLR antibody (AA 47-574)

Catalog No. ABIN5775967

The Mouse Monoclonal anti-PKLR antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect PKLR in samples from Human.

Quick Overview for PKLR antibody (AA 47-574) (ABIN5775967)

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PKLR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT1E3

Product Details anti-PKLR Antibody

Binding Specificity: AA 47-574

Immunogen: Recombinant human PKLR (47-574aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for PKLR

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Alternative Name: PKLR

Background: PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young.

NCBI Accession: NP_000289

Pathways: Ribonucleoside Biosynthetic Process