NCR3 antibody (AA 19-138)

Catalog No. ABIN5776033

The Mouse Monoclonal anti-NCR3 antibody is suitable to detect NCR3 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for NCR3 antibody (AA 19-138) (ABIN5776033)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: AT38D9

Product Details anti-NCR3 Antibody

Binding Specificity: AA 19-138

Purpose: Human NKp30/NCR3 antibody

Purification: Purified

Immunogen: Recombinant human NCR3 (19-138aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NKp30/NCR3

Background: NCR3, also known as NKP30, is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_001138939

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process