ANGPTL3 antibody (AA 243-460)

Catalog No. ABIN5776056

This Mouse Monoclonal antibody specifically detects ANGPTL3 in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for ANGPTL3 antibody (AA 243-460) (ABIN5776056)

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ANGPTL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT23D8

Product Details anti-ANGPTL3 Antibody

Binding Specificity: AA 243-460

Purpose: Human Angiopoietin-like Protein 3/ANGPTL3 antibody

Purification: Purified

Immunogen: Recombinant human ANGPT5 (243-460aa) purified from E. coli.

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Alternative Name: Angiopoietin-like Protein 3/ANGPTL3

Background: ANGPTL3 also known as Angiopoietin-related protein 3 is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN) -like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.

NCBI Accession: NP_055310