BRCC3 antibody (AA 1-316)

Catalog No. ABIN5776068

This Mouse Monoclonal antibody specifically detects BRCC3 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for BRCC3 antibody (AA 1-316) (ABIN5776068)

Target: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRCC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT3B1

Product Details anti-BRCC3 Antibody

Binding Specificity: AA 1-316

Purpose: Human BRCC36/BRCC3 antibody

Purification: Purified

Immunogen: Recombinant BRCC36 (1-316aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for BRCC3

Target: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Alternative Name: BRCC36/BRCC3

Background: BRCC36 (BRCA1/BRCA2-containing complex, subunit 36) is a holoenzyme complex containing BRCA1, BRCA2. BRCC36 is an ubiquitin E3 ligase complex that has a role in DNA repair and enhances cellular survival following DNA damage. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.

NCBI Accession: NP_077308

Pathways: Positive Regulation of Response to DNA Damage Stimulus