KRT8 antibody (AA 1-483)

Catalog No. ABIN5776086

This Mouse Monoclonal antibody specifically detects KRT8 in WB, IF, FACS, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for KRT8 antibody (AA 1-483) (ABIN5776086)

Target: KRT8 (Keratin 8 (KRT8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: AT3D11

Product Details anti-KRT8 Antibody

Binding Specificity: AA 1-483

Immunogen: Recombinant human KRT8 (1-483aa) purified from E. coli

Isotype: IgG3 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: Keratin 8/KRT8

Background: Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

NCBI Accession: NP_002264