Fascin antibody (AA 1-493)

Catalog No. ABIN5776189

The Mouse Monoclonal anti-Fascin antibody has been validated for WB, FACS, IF, ELISA and ICC. It is suitable to detect Fascin in samples from Human.

Quick Overview for Fascin antibody (AA 1-493) (ABIN5776189)

Target: Fascin (FSCN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Clone: AT13D2

Product Details anti-Fascin Antibody

Binding Specificity: AA 1-493

Purpose: Human Fascin/FSCN1 antibody

Purification: Purified

Immunogen: Recombinant human FSCN1 (1-493aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin/FSCN1

Background: FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.

NCBI Accession: NP_003079