CAPG antibody (AA 1-348)

Catalog No. ABIN5776213

The Mouse Monoclonal anti-CAPG antibody is suitable to detect CAPG in samples from Human. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for CAPG antibody (AA 1-348) (ABIN5776213)

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CAPG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1D10

Product Details anti-CAPG Antibody

Binding Specificity: AA 1-348

Purpose: Human CapG antibody

Purification: Purified

Immunogen: Recombinant human CAPG (1-348aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CAPG

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Alternative Name: CapG

Background: Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments.

Pathways: Regulation of Actin Filament Polymerization