GALE antibody (AA 1-348)

Catalog No. ABIN5776219

The Mouse Monoclonal anti-GALE antibody is suitable to detect GALE in samples from Human. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for GALE antibody (AA 1-348) (ABIN5776219)

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GALE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT6G10

Product Details anti-GALE Antibody

Binding Specificity: AA 1-348

Purpose: Human UDP-galactose-4-epimerase/GALE antibody

Purification: Purified

Immunogen: Recombinant human GALE (1-348aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Alternative Name: UDP-galactose-4-epimerase/GALE

Background: The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity. Additionally, human and some bacterial GALE isoforms reversibly catalyze the formation of UDP-N-acetylgalactosamine (UDP-GalNAc) from UDP-N-acetylglucosamine (UDP-GlcNAc) in the presence of NAD+, an initial step in glycoprotein or glycolipid synthesis.

NCBI Accession: NP_000394

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process