PDIA3 antibody (AA 25-505)

Catalog No. ABIN5776230

This Mouse Monoclonal antibody specifically detects PDIA3 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for PDIA3 antibody (AA 25-505) (ABIN5776230)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDIA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT9E9

Product Details anti-PDIA3 Antibody

Binding Specificity: AA 25-505

Immunogen: Recombinant human PDIA3 (25-505aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Alternative Name: GRP58/PDIA3

Background: PDIA3, also known as protein disulfide-isomerase A3, is a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. This protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

NCBI Accession: NP_005304

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis