PNPO antibody (AA 57-261)

Catalog No. ABIN5776245

This Mouse Monoclonal antibody specifically detects PNPO in WB, ELISA, IHC, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for PNPO antibody (AA 57-261) (ABIN5776245)

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PNPO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT2C7

Product Details anti-PNPO Antibody

Binding Specificity: AA 57-261

Purpose: Human PNPO antibody

Purification: Purified

Immunogen: Recombinant human PNPO (57-261aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PNPO

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Alternative Name: PNPO

Background: PNPO (pyridoxamine 5'-phosphate oxidase) is a 261 amino acid protein belonging to the pyridoxamine 5'-phosphate oxidase family. It is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.

NCBI Accession: NP_060599