TXNRD1 antibody (AA 161-647)

Catalog No. ABIN5776265

Product Details anti-TXNRD1 Antibody

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Binding Specificity: AA 161-647

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Immunogen: Recombinant human TXNRD1 (161-647aa) purified from E. coli

Clone: AT30F1

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: Thioredoxin Reductase 1/TRXR1 (TXNRD1 Products)

Background: TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.

NCBI Accession: NP_001087240

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis