EGFR antibody

Catalog No. ABIN594831

The Mouse Monoclonal anti-EGFR antibody (ABIN594831) specifically detects EGFR in IF, IP and Func. The antibody is reactive with Human samples.

Quick Overview for EGFR antibody (ABIN594831)

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EGFR antibody is un-conjugated

Application: Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)

Product Details anti-EGFR Antibody

Specificity: Recognizes a protein determinant of the extra cellular domain of the human Epidermal Growth Factor Receptor. Does not cross-react with mouse. Shows binding competition with EGF.

Purification: Purified

Immunogen: Epidermal Growth Factor Receptor.

Isotype: IgG1

Application Details

Application Notes: Approved: Func, IF, IP

Usage: Suitable for use in Immunofluorescence, Immunoprecipitation, Immunogold labeling and electron microscopy. Immunoprecipitation: Reacts with functional EFR protein-tyrosine kinase complex.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 1 % BSA, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for EGFR

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name: EGFR

Background: Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

Gene ID: 1956

UniProt: P00533

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins