Puumala Hantavirus (PUUV) antibody

Catalog No. ABIN5954764

Cited in 7+ publications. The Mouse Monoclonal anti-Puumala Hantavirus antibody (Clone A1C5) (ABIN5954764) specifically detects Puumala Hantavirus in IHC, WB, ICC and IF. The antibody is reactive with Puumala hantavirus samples.

Quick Overview for Puumala Hantavirus (PUUV) antibody (ABIN5954764)

Target: Puumala Hantavirus (PUUV)

Reactivity: Puumala hantavirus

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: A1C5

Product Details

Cross-Reactivity (Details): Puumala virus-infected cells

Characteristics: The antibody is directed against the Puumala serotype nucleocapsid protein which has been shown to be the major immunogen in infections (HFRS, Nephropathia epidemica) caused by Puumala Virus. Positive cross-reaction with Sin Nombra Virus (SNV).No coss-reactivity

Purification: supernatant

Immunogen: recombinant Puumala nucleocapsid protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: contains 0.09 % sodium azide

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage: 4 °C,-20 °C

storageComment: short term at 2 - 8 °C, long term storage in aliquots at - 20 °C, avoid freeze/ thaw cycles

References

Gallo, Kotlik, Roingeard, Monot, Chevreux, Ulrich, Tordo, Ermonval: "Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction." in: PLoS neglected tropical diseases, Vol. 16, Issue 10, pp. e0010844, (2022) (PubMed).

Vietzen, Hartenberger, Aberle, Puchhammer-Stöckl: "Dissection of the NKG2C NK cell response against Puumala Orthohantavirus." in: PLoS neglected tropical diseases, Vol. 15, Issue 12, pp. e0010006, (2022) (PubMed).

Hägele, Müller, Nusshag, Reiser, Zeier, Krautkrämer: "Motility of human renal cells is disturbed by infection with pathogenic hantaviruses." in: BMC infectious diseases, Vol. 18, Issue 1, pp. 645, (2019) (PubMed).

Hägele, Müller, Nusshag, Reiser, Zeier, Krautkrämer: "Virus- and cell type-specific effects in orthohantavirus infection." in: Virus research, Vol. 260, pp. 102-113, (2019) (PubMed).

Pettersson, Rasmuson, Andersson, Ahlm, Evander: "Hantavirus-specific IgA in saliva and viral antigen in the parotid gland in patients with hemorrhagic fever with renal syndrome." in: Journal of medical virology, Vol. 83, Issue 5, pp. 864-70, (2011) (PubMed).

Krautkrämer, Zeier: "Hantavirus causing hemorrhagic fever with renal syndrome enters from the apical surface and requires decay-accelerating factor (DAF/CD55)." in: Journal of virology, Vol. 82, Issue 9, pp. 4257-64, (2008) (PubMed).

Khattak, Darai, Rösen-Wolff: "Puumala virus nucleocapsid protein expressed in transgenic plants is not immunogenic after oral administration." in: Virus genes, Vol. 29, Issue 1, pp. 109-16, (2004) (PubMed).

Target Details

Target: Puumala Hantavirus (PUUV)

Alternative Name: Hantavirus Puumala

Target Type: Virus