Glutamate Receptor 1 antibody (Ser849)

Catalog No. ABIN5955606

The Rabbit Polyclonal anti-Glutamate Receptor 1 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect Glutamate Receptor 1 in samples from Human, Rat and Mouse.

Quick Overview for Glutamate Receptor 1 antibody (Ser849) (ABIN5955606)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: Ser849

Specificity: GLUR 1, GLUR A,AMPA 1,AMPA selective glutamate receptor 1,AMPA-selective glutamate receptor 1,GluA1,GLUH1,GluR K1,GluR-1,GluR-A,GluR-K1,GLUR1,GLURA,GluRK1,Glutamate receptor 1,Glutamate receptor ionotropic AMPA 1,Glutamate receptor ionotropic,Glutamate receptor,ionotropic,AMPA 1,Gria1,GRIA1,HBGR1,MGC133252,OTTHUMP00000160643,OTTHUMP00000165781,OTTHUMP00000224241,OTTHUMP00000224242,OTTHUMP00000224243

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human GluR-1 around the non-phosphorylation site of Ser849.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluR-1

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 102kDa

Gene ID: 2890

UniProt: P42261

Pathways: PI3K-Akt Signaling