PPP2CA antibody (Tyr307)

Catalog No. ABIN5956413

The Rabbit Polyclonal anti-PPP2CA antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect PPP2CA in samples from Human, Mouse and Rat.

Quick Overview for PPP2CA antibody (Tyr307) (ABIN5956413)

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2CA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PPP2CA Antibody

Binding Specificity: Tyr307

Specificity: PP2A alpha,PP2A-alpha,PP2AA,PP2Aalpha,PP2Ac,PP2CA,PP2Calpha,PPP2CA,Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform,Protein phosphatase 2 catalytic subunit alpha isoform,Protein phosphatase 2,catalytic subunit,alpha isozyme,Protein phosphatase 2A catalytic subunit,alpha isoform,Replication protein C,RP C,RP-C,RPC,Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform,Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human PP2A-Calpha around the non-phosphorylation site of Tyr307.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Alternative Name: PP2A-Calpha

Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.

Molecular Weight: 36kDa

Gene ID: 5515

UniProt: P67775

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades