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EEF2K antibody (Ser366)
This Rabbit Polyclonal antibody specifically detects EEF2K in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Rat.
Quick Overview for EEF2K antibody (Ser366) (ABIN5959454)
Target
See all EEF2K Antibodies
EEF2K
(Eukaryotic Elongation Factor-2 Kinase (EEF2K))
Reactivity
All reactivities for EEF2K antibodies
Human, Rat
Host
All hosts for EEF2K antibodies
Rabbit
Clonality
All clonalities for EEF2K antibodies
Polyclonal
Conjugate
All conjugates for EEF2K antibodies
This EEF2K antibody is un-conjugated
Application
All applications for EEF2K antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Product Details anti-EEF2K Antibody
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Binding Specificity
All epitopes for EEF2K antibodies
Ser366
Specificity
C86191,Calcium/calmodulin dependent eukaryotic elongation factor 2,Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase,Calmodulin dependent protein kinase III,cb365,EC 2.7.11.20,eEF 2 kinase,eEF 2K,eEF-2 kinase,eEF-2K,Eef2k,EEF2K protein,EF2K,Elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase,fa04b08,HSU93850,kinase eEF2K,MGC45041,SMEF2K,wu:fa04b08,zgc:100973
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human eEF2K around the non-phosphorylation site of Ser366.
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for EEF2K
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Target
EEF2K
(Eukaryotic Elongation Factor-2 Kinase (EEF2K))
Alternative Name
eEF2K
Background
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Molecular Weight
82kDa
Gene ID
29904
UniProt
O00418
Pathways
AMPK Signaling
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