EEF2K antibody (pSer366)

Catalog No. ABIN7250797

Product Details anti-EEF2K Antibody

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Binding Specificity: pSer366

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF2K antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Phosphorylated antibody

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Alternative Name: EEF2K (EEF2K Products)

Synonyms: HSU93850 antibody, eEF-2K antibody, C86191 antibody, SMEF2K antibody, eEF-2 kinase antibody, cb365 antibody, fa04b08 antibody, wu:fa04b08 antibody, zgc:100973 antibody, eukaryotic elongation factor 2 kinase antibody, eukaryotic elongation factor-2 kinase antibody, EEF2K antibody, Eef2k antibody, eef2k antibody, LOC101930123 antibody

Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Molecular Weight:

Observed_MW: 105 kDa

Calculated_MW: 82 kDa

UniProt: O00418

Pathways: AMPK Signaling