EEF2K antibody (AA 201-500)

Catalog No. ABIN7152101

Product Details anti-EEF2K Antibody

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Binding Specificity: AA 201-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF2K antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic elongation factor 2 kinase protein (201-500AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Alternative Name: EEF2K (EEF2K Products)

Synonyms: HSU93850 antibody, eEF-2K antibody, C86191 antibody, SMEF2K antibody, eEF-2 kinase antibody, cb365 antibody, fa04b08 antibody, wu:fa04b08 antibody, zgc:100973 antibody, eukaryotic elongation factor 2 kinase antibody, eukaryotic elongation factor-2 kinase antibody, EEF2K antibody, Eef2k antibody, eef2k antibody, LOC101930123 antibody

Background:

Background: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Aliases: C86191 antibody, Calcium/calmodulin dependent eukaryotic elongation factor 2 antibody, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase antibody, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase antibody, Calmodulin dependent protein kinase III antibody, cb365 antibody, EC 2.7.11.20 antibody, eEF 2 kinase antibody, eEF 2K antibody, eEF-2 kinase antibody, eEF-2K antibody, Eef2k antibody, EEF2K protein antibody, EF2K_HUMAN antibody, Elongation factor 2 kinase antibody, Eukaryotic elongation factor 2 kinase antibody, fa04b08 antibody, HSU93850 antibody, kinase eEF2K antibody, MGC45041 antibody, SMEF2K antibody, wu:fa04b08 antibody, zgc:100973 antibody

UniProt: O00418

Pathways: AMPK Signaling