Integrin beta 3 antibody (pTyr773)

Catalog No. ABIN596000

The Rabbit Polyclonal anti-Integrin beta 3 antibody has been validated for WB, IHC and IHC (p). It is suitable to detect Integrin beta 3 in samples from Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Rabbit, Sheep, Horse and Chicken.

Quick Overview for Integrin beta 3 antibody (pTyr773) (ABIN596000)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Rabbit, Sheep, Horse, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Integrin beta 3 Antibody

Binding Specificity: pTyr773

Specificity: Recognizes human Integrin, beta3 when phosphorylated at tyrosine 773. Species cross-Reactivity: mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human Integrin beta3 around the phosphorylation site of tyrosine 773 (P-L-YP-K-E).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot:1:500-1:1000. Immunohistochemistry:1:50-1:100. Antibody was tested in IHC using FFPE human breast carcinoma tissues.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3 / Integrin Beta 3 / CD61

Background: Name/Gene ID: ITGB3
Family: Integrin

Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex