SOX9 antibody (Ser181)

Catalog No. ABIN5960080

This anti-SOX9 antibody is a Rabbit Polyclonal antibody detecting SOX9 in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for SOX9 antibody (Ser181) (ABIN5960080)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SOX9 Antibody

Binding Specificity: Ser181

Specificity: Campomelic dysplasia autosomal sex reversal,CMD 1,CMD1,CMPD 1,CMPD1,SOX 9,Sox9,SOX9,SRA 1,SRA1,SRXX2,SRXY10,SRY (sex determining region Y) box 9 (campomelic dysplasia autosomal,SRY (sex determining region Y) box 9,SRY (sex determining region Y)-box 9,SRY (sex-determining region Y)-box 9 protein,SRY related HMG box gene 9,Transcription factor SOX 9,Transcription factor SOX-9,transcription factor SOX9

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Sox-9 around the non-phosphorylation site of Ser181.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: Sox-9

Background: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Molecular Weight: 56kDa

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development