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CHEK2 antibody (Thr383)

The Rabbit Polyclonal anti-CHEK2 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect CHEK2 in samples from Human, Mouse, Rat and Monkey.

Catalog No. ABIN5961579

Datasheet as PDF

Quick Overview for CHEK2 antibody (Thr383) (ABIN5961579)

Target

See all CHEK2 Antibodies

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity

Human, Mouse, Rat, Monkey

Host

Rabbit

Clonality

Polyclonal

Conjugate

This CHEK2 antibody is un-conjugated

Application

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product CHEK2 Primary Antibody

Binding Specificity
26

25

19

17

16

16

15

15

9

8

8

8

6

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Thr383

Specificity

CDS 1,Cds1,Cds1 homolog,Checkpoint kinase 2,Checkpoint like protein CHK2,CHEK 2,Chek2,Chk 2,CHK2 checkpoint homolog (S. pombe),CHK2 checkpoint homolog,CHK2,hCds1,HuCds 1,LFS 2,LFS2,PP1425,RAD 53,RAD53,Rad53 homolog,Serine/threonine protein kinase Chk2,Serine/threonine-protein kinase Chk2

Purification

Affinity purification

Immunogen

Synthesized peptide derived from human Chk2 around the non-phosphorylation site of T383.

Isotype

IgG
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibody
CHEK2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB19067 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Dog WB, IHC, IP, IHC (p), FACS Host: Mouse Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Dog WB, IHC, IF, IP, IHC (p), FACS Host: Mouse Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Monkey, Dog WB, IHC, IF, IHC (p), FACS Host: Mouse Monoclonal 10G7 unconjugated

Application Notes

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Restrictions

For Research Use only
Concentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Alternative Name

Chk2

Background

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

Molecular Weight

61kDa

Gene ID

11200

UniProt

O96017

Pathways

p53 Signaling, Apoptosis, Cell Division Cycle