FLT1 antibody (pTyr1048)

Catalog No. ABIN5961614

This Rabbit Polyclonal antibody specifically detects FLT1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FLT1 antibody (pTyr1048) (ABIN5961614)

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FLT1 Antibody

Binding Specificity: pTyr1048

Specificity: EC 2.7.10.1,FLT 1,FLT,Flt-1,FLT1,Fms like tyrosine kinase 1,Fms related tyrosine kinase 1,Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor),Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor,Fms-like tyrosine kinase 1,FRT,Soluble VEGF receptor 1 14,Soluble VEGFR1 variant 2,Soluble VEGFR1 variant 21,Tyrosine protein kinase FRT,Tyrosine protein kinase receptor FLT,Tyrosine-protein kinase FRT,Tyrosine-protein kinase receptor FLT,Vascular endothelial growth factor receptor 1,Vascular endothelial growth factor vascular permeability factor receptor,Vascular permeability factor receptor 1,Vascular permeability factor receptor,VEGFR 1,VEGFR-1,VEGFR1,VGFR1

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Flt-1 around the phosphorylation site of Tyr1048

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Alternative Name: Flt-1

Background: Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Molecular Weight: 151kDa

Gene ID: 2321

UniProt: P17948

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals